Tuesday, June 16, 2009

Fatty liver worsened by leaky gut and bacterial overgrowth

Research published in the June issue of the journal Hepatology has found patients with an advanced form of fatty liver are more likely to have increased intestinal permeability and bacterial overgrowth in their small intestine. The severity of these intestinal conditions correlates with the severity of fatty liver.

Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the world. It affects one in five to one in three people in western nations. It occurs when excessive fat accumulates within the liver, and can lead to inflammation, scarring and even eventual cirrhosis of the liver.

Poor diet is the main cause of fatty liver disease; it occurs in people who are overweight (particularly on their abdomen), diabetics and people who eat a lot of sugar.

Risk factors for developing fatty liver disease include:

* Obesity
* High carbohydrate diet (sugar, breakfast cereals and foods made of flour)
* Diabetes and Syndrome X (insulin resistance)
* High alcohol intake
* Side effect of some medication
* Autoimmune liver disease

In the early stages of fatty liver, excess fat accumulation is the only change that occurs. However, if left to progress, the liver may develop a type of hepatitis, which causes inflammation inside the liver. This inflammation greatly increases the risk of permanent liver damage. Research has shown that people with “leaky gut syndrome” and high levels of harmful bacteria in their small intestine are far more prone to developing a dangerous form of fatty liver disease.

Leaky gut syndrome occurs when the mucous lining of the intestines becomes irritated and inflamed, making it more porous than it should be. This allows undigested food molecules, bacteria (and their toxins), fungi and other toxins to gain entry into your bloodstream. All blood from the intestines travels to the liver first. If the bowel is toxic, this means a great deal of toxic waste is delivered to the liver each day.

Researchers believe that it is the toxins secreted by gram-negative bacteria in the small intestine (called lipopolysaccharides) that cause most harm to the liver. These toxins stimulate immune cells within the liver, which causes wear and tear, inflammation and tissue damage in the liver.

More about leaky gut syndrome

So how do you know if you have leaky gut syndrome or an overgrowth of bad bacteria? The following symptoms are good indicators:

* Food allergies
* Eczema
* Abdominal bloating after eating
* Indigestion, heartburn or reflux
* Constipation or diarrhea
* Flatulence or burping

These symptoms are extremely common, however they should not be ignored. The health of your gut has an enormous impact on your whole body. The concept that increased intestinal permeability and bad bugs in the gut can contribute to disease was first proposed in 1890 by Llewellyn Jones, who published “Theory of auto-intoxication from gut bacteria”. That statement is very true; we do poison ourselves if we have the wrong gut bacteria inside us.

Intestinal Parasite Cleanse capsules contain powerful herbs that are effective at destroying harmful gut bacteria. This product should be followed by a good probiotic (beneficial bacteria) and a liver tonic like Livatone Plus.

Our book called The Ultimate Detox contains strategies to repair leaky gut syndrome, as well as improve liver health. If you have a fatty liver please be aware that it is reversible in the early stages. Follow our guidelines for liver health on our website, but also be aware of improving your intestinal health.


Luca Miele, Venanzio Valenza, et al. Increased intestinal permeability and tight junction alterations in non-alcoholic fatty liver disease. Hepatology 2009;49:1877-1887


  1. I am surprised to hear that fatty liver are more likely to have increased intestinal permeability and bacterial overgrowth in their small intestine. Thanks for sharing such information here in this site.

  2. Reducing or eliminating alcohol use can improve fatty liver due to alcohol toxicity. Controlling blood sugar may reduce the severity of fatty liver in patients with diabetes. Ursodeoxycholic acid may improve liver function test results, but its effect on improving the underlying liver abnormality is unclear.


  3. could fatty liver have anything to do with the removal of gall bladder?

  4. How can we possibly prevent leaky gut?

  5. I just found out I have fatty liver. I am allergic to sulpha drugs and get heartburn and intestinal issues from eating sulpher bearing foods like garlic. Is there a connection here? Can I just skip those?

  6. I have a 2 year old little girl, who for the past year has had severe constipation. She can no longer go on her own and always asks for "help" we have to hold her and in teh end if she just cant do it we give her a suppository to help her. Her poo is extremely hard and i can only liken it to a rock, it is exteremly large for a 2 year old. We have increased fibre, water fruit tried all the prune juices and consitpation drugs available for her age, but nothing is working? Couls this be a connection to leaky gut? I really need answers, i just keep getting told to increase water and fruit and fiber but there is only so much you can get a 2 year old to do. She is terrified to use the toilet now and I am worried this is causing further damage to her insides.... do you have any suggestions?

  7. I've had the problem of constipation for years. I also have diverticulosis - not a very good combination.

    I've found that taking capsules of Magnesium keeps my stool soft. I'm an old fat guy 300+ pounds and take 1,500 to 2,000 mg of magnesium daily.

    Of course it would be much less for a little two year old.

    Magnesium capsules are available at most any drug store and are not expensive.

  8. I was surprised to know constipation is a symptoms because I really hate to have it. All I know is that constipation makes you suffer and have a bad day.

  9. Thanks for this information. I had no idea what leaky gut syndrome was or how it related to fatty liver. Just one more thing to be aware of as you work on reducing fat in your liver. It's good to know a proper diet and exercise are good combatants against FLD.

  10. I had a friend that he had this disease and he died some weeks ago because he couldn't stop to drink alcohol and many doctors told him that if he keep drinking he will die but he didn't want to obey.

  11. Is important to know what happens with our body when we live with to much excess, like have overweight we should think about all that things, very good blog

  12. I like all your posts but this information isn't clear for me I will try to research information regarding the issue because I am really interested about this... I would like to know where I could found more about?

  13. costiveness is a common cause of painful defecation.Severe constipation includes failure to pass stools or gas.I believe that constipation results from the kind of food one eat and especially when you have no diet plan. thanks for sharing, it was a privilege to read such an educative article.

  14. I just read your article and it amazes me that diabetes could be one of the risk factors of NAFLD. This is a new information to me though that needs to be shared.

    And to avoid the risks of having such illness, We must follow a healthy diet and a healthy lifestyle.

  15. Wonderful post. The symptoms you have listed are really common. Basically, I'd have one of those in a month. How do we know that we are looking at the same problem?

  16. And all the while I thought that you can only mess your liver by alcohol never though poor eating habits is a main reason of liver disease.

  17. very well written please share more about Autoimmune liver disease.

  18. Very informative posts :) I wish you success in your book "The Ultimate Detox." I hope to hear some of the strategies to reverse leaky gut syndrome. Keep the posts coming!

  19. To keep our liver healthy as the blog have suggested the causes for fatty liver we should always take a low calorie and cholesterol free diet.This is the best way to have healthy liver .
    Pneumonia Contagious

  20. Your bloody brilliant!
    PA, USA

  21. Τhese ingrеԁients аlso function collеctivеlу
    tο aѕѕistance lighten the
    sκin and hold the all round look naturаl anԁ constant.

    Тake a lоoκ аt mу wеb page;
    Trilastin Reviews

  22. Do adsense people mind merely publish articles whcih aren't copyrighted?

    Visit my web page; Paginasamarillas-Atl.Com

  23. What is a natural way to increase my penis size?

    Check out my weblog: sizegenetics review

  24. The type of software that an online casino uses determines its level of fairness and security.
    The only disadvantage of online casino can be easily resolved.

    I read a few websites and watched a few videos on
    You Tube about how to do this. My name is Mason (22 years old) and my hobbies are Seashell Collecting and Baton

    Here is my blog post; international removals

  25. Goood way of explaining, and pleasant article to obtain facts on tthe topic of
    my presentation subject matter, which i amm going to deliver in institution of higher education.

    Look at my site: win pick 3, ,

  26. , at other times smashing the windows of cars and churches. He was put on strong medication, but it proved difficult to calibrate. At one point when his demons returned, he began going over to the Jobs house in the evenings, throwing rocks through the windows, leaving rambling letters, and once tossing a firecracker into the house. He was arrested, but the case was dropped when he went for michael kors bag more treatment. ��Burrell was so funny and na?ve, and then one April day he suddenly snapped,�� Jobs recalled. ��It was the weirdest, saddest thing.��